期刊文献+

炎症状态与原发性高血压患者动态脉压的关系 被引量:12

原文传递
导出
摘要 目的探讨炎症状态与原发性高血压患者动态脉压(PP)的关系。方法对原发性高血压患者194例进行动态血压监测,按动态PP分为24h平均PP<40mmHg组(PP1组,n=66)、24h平均PP在40~60mmHg之间组(PP2组,n=67)、24h平均PP>60mmHg组(PP3组,n=61),正常对照组(n=30)。分别用免疫比浊法测定血浆C反应蛋白(CRP),用放免法测定血浆肿瘤坏死因子α(TNF-α)、白介素6(IL-6)。比较各组之间血浆CRP、TNF-α及IL-6水平并进行各指标之间相关分析。结果血浆CRP、TNF-α及IL-6水平在原发性高血压患者升高,随PP增高而进一步升高;动态PP与血浆CRP、TNF-α、IL-6呈正相关。结论炎症因素可能与原发性高血压患者动态PP升高有一定的关系。
出处 《中华高血压杂志》 CAS CSCD 北大核心 2009年第2期171-172,共2页 Chinese Journal of Hypertension
  • 相关文献

参考文献6

二级参考文献53

  • 1马文君,刘国仗.老年人高血压靶器官损害特点[J].中华老年医学杂志,2005,24(4):255-255. 被引量:13
  • 2王鲁雁,孙宁玲.高敏C反应蛋白与高血压病患者合并颈动脉粥样硬化的关系[J].中华老年心脑血管病杂志,2006,8(1):19-21. 被引量:20
  • 3陈明,胡申江,张健,张新满,周永列.不同危险度的高血压病人血管内皮功能[J].高血压杂志,2006,14(4):257-260. 被引量:24
  • 4[1]Dahlia Weitzman,Uri Goldbourt.The significance of various bood pessure indices for long-term stroke,coronary heart disease,and all-cause mortality in men:the Israeli ischemic heart disease study[J].Stroke,2006,37:358-363.
  • 5中国高血压防治指南修订版.中国高血压防治指南(2005年修订出版)[J].高血压杂志,2005,(13):18-42.
  • 6[5]He J,Gu D,Wu X,et al.Major causes of death among menand women in China[J].N Engl J Med,2005,353:1124-1134.
  • 7[6]Athanase B,Annie R,Michel S,et al.Pulse pressure and cardiovascular mortality in normotensive and hypertensive subjects[J].Hypertension,1998,32:560-564.
  • 8[8]PaoloV,Giuseppe S,Gianpaolo R,et al.Different prognostic impact of 24 h mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hypertension[J].Circulation,2001,103:2579-2584.
  • 9[10]Tsivgoulis G,Spengos K,Zakopoulos N,et al.Twenty four hour pulse predicts long term recurrence in acute stroke patients[J].J Neurol Neurosurg Psychiatry,2005,76:1360-1365.
  • 10[12]Lovett JK,Howard SC,Rothwell PM.Pulse pressure is independently associated with carotid plaque ulceration[J].J Hypertens,2003,21:1669-1676.

共引文献204

同被引文献88

  • 1林雪,雷震云,余承云,任玉汝,张颖.虚燥更平颗粒对女性更年期高血压血压变异性的影响[J].新疆医科大学学报,2008,31(12):1753-1756. 被引量:15
  • 2任军梅,王瑞英,黄淑田.老年原发性高血压患者动态脉压与高敏C-反应蛋白相关性[J].中国心血管杂志,2006,11(1):28-31. 被引量:10
  • 3张钦凤,朴鍾龜,高尚伯,金春培,张世鎮.脉压与心脑血管病的关系:一个大样本的随访研究[J].中华高血压杂志,2006,14(10):830-832. 被引量:25
  • 4屈正俊,骆勤正,彭丽春,房明昌.高敏C反应蛋白及脉压与老年高血压患者动脉粥样硬化相关性探讨[J].中华老年心脑血管病杂志,2007,9(1):20-22. 被引量:20
  • 5Blake GJ, Ridker PM. Novel clinical markers of vascular wall inflammation[J]. Circ Res, 2001,89(9) : 763-771.
  • 6Charbonneau F, Anderson TJ, Title L, et al. Modulation of arterial reactivity using amlodipine and atorvastatin measured by ultrasound examination[J]. Atherosclerosis, 2008,197 (1): 420-427.
  • 7Philippe F,Chemaly E, Blaeher J,et al. Aortic pulse pressure and extent of coronary artery disease in percutaneous translum inal coronary angioplasty candidates [J]. Am J Hypertens, 2002,15(8):672-677.
  • 8Kuklinska AM, Mroczko B, Musial WJ, et al. High-sensitivity C-reactive protein and total antioxidant status in patients with essential arterial hypertension an6 dyslipidemia. [J]. Adv Med Sei, 2009,54 (2) : 225-232.
  • 9Ridker PM. High-sensitivity C-reactive protein: potential adjunct for global risk assessmeatin the primary prevention of cardiovascular disease [J] Circulation, 2001,103 ( 13 ) : 1813- 1818.
  • 10Chappell DC, Vatner SE, Nerem RM, et al. Oscillatory shear stress stimulates adhesion molecule expressure in culeured human endothelium[J]. Circ Res, 1998,82(5) : 532-539.

引证文献12

二级引证文献53

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部