中西药结合治疗急性大面积脑梗死的临床疗效观察

Clinical Observation of Treatment of Acute Massive Cerebral Infarction with Integrative Chinese and Western Medicine

目的:探索提高治疗急性大面积脑梗死临床疗效的途径。方法:将48例患者随机分为治疗组和对照组。对照组24例,采用常规西医脱水降颅压、脑保护、抗血小板聚集、改善循环及对症支持等治疗;治疗组24例,采用常规西医治疗配合中药灌肠。28天后统计疗效。结果:治疗组总有效率为79.8%,对照组总有效率为53.6%,经统计学处理,组间差异有显著性意义(P<0.05)。美国国立卫生研究院卒中量表(NIHSS)评分治疗组明显优于对照组(P<0.05)。昏迷量表(GCS)评分治疗组明显优于对照组(P<0.05)。结论:中西药结合治疗大面积脑梗死明显优于单纯西医治疗,能明显改善患者的神经功能缺损程度,降低死亡率。

Objective：to explore effective treatments for acute massive cerebral infarction. Methods： Forty-eight patients were randomly divided to treatment group and control group. Twenty-four patients of the control group were given routine western medicine treatment, such as reducing intracranial pressure using dehydrator, cerebral protection, anti-platelet aggregation,blood circular improvement, and symptomatic therapy ; The 24 patients of the treatment group were given enema of Chinese medicine in addition to western medicine treat- ment. Effect was observed 28 days later. Results：the total effective rate for treatment group was 79.8% with a significant difference to 53.6% of the control group （ P 〈 0. 05）. Treatment group also scored significantly higher at National Institute of Health Stroke Scale （NIHSS） （ P 〈 0. 05 ） and Glasgow Coma Scale （GCS） （ P 〈 O. 05 ）. Conclusion： Integrative treatments of Chinese and western medicine is superior to simple western treatment, and can remarkably reduce neurologic impairment and death rate.