米非司酮对非根治性手术术后内膜异位症观察

Observation of mifepristone and non-radical operation in the treatment of endometriosis

目的研究米非司酮对非根治性手术子宫内膜异位症术后内膜异位症(EM)临床疗效观察。方法93例患者分为米非司酮组和对照组,比较两组的临床疗效及副反应。结果米非司酮对痛经、下腹痛或腰骶疼痛及性交痛等症状控制率有明显提高,两组比较,用药组的征状、体征改善情况明显优于对照组(P<0101)。结论内异症术后加用米非司酮可提高临床症状控制率,复发率低,妊娠率高,故术后加用米非司酮是治疗内异症的较好途径。

Objective： To Observe the effect of mifepristone after non-radical operation in the treatment of endometriosis. Methods： 93 cases were divided into 2 groups randomly, the treated group （n=53） received the treatment of non-radical operation and mifepristone., the control group only received operation, the clinical effect and adverse effect were compared between two groups. Results： The treated group was better than control group at improving symptoms, such as alleviation of dysmenorrhoea, hypogastralgia, lumbesacral algesia and intercourse pain（P 〈 0.01）. Conclusion： The combination of non-radical operation with mifepristone is the better treatment in endomctriosis.