摘要
目的了解临床分离的大肠埃希菌耐药性和耐消毒剂基因存在状况。方法测定临床连续分离60株大肠埃希菌对19种抗菌药物的敏感性及产超广谱β-内酰胺酶(ESBLs)情况。采用聚合酶链反应检测qacE△1基因。结果60株大肠埃希菌对亚胺培南/西司他丁、美罗培南、头孢哌酮/舒巴坦3种抗菌药物完全敏感,对其余16种抗菌药物耐药率在5.0%～90.0%,ESBLs检出率为45.0%;qacE△1基因阳性34株(阳性率56.7%)。结论大肠埃希菌具多药耐药特征,qacE△1基因携带率高。
OBJECTIVE To investigate the resistance and the disinfectant-resistant genes of chlorhexidine-sulfadiazine-resistant Escherichia coli isolates from hospitalized patients in the Lishui People＇s Hospital. METHODS Microdilute tests were performed to detect susceptibility to 19 kinds of antimicrohial agents in 60 E. coli strains, and the qacE△1 gene was detected by PCR. RESULTS The resistant rates to other antimicrobial agents arranged in 5.0-90.0%. The prevalence of ESBLs in isolates was 45.0%. qacE△1 Gene was 56. 7%. CONCLUSIONS The 60 strains are multiple-drug-resistant. There are very high positive percentages of qacE△1 gene in E. coli isolates from the hospital.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第3期247-249,共3页
Chinese Journal of Nosocomiology
关键词
大肠埃希菌
耐药性
耐消毒剂基因
Escherichia coli
Drug-resistance
Disinfectant-resistant genes
