住院患者下呼吸道感染抗菌药物应用调查

Antibiotics Usage in Inpatients with Lower Respiratory Infections

目的调查呼吸内科住院患者抗菌药物使用情况,为临床合理应用抗菌药物提供依据。方法采用回顾性方法,抽查呼吸内科下呼吸道感染病历224份,对抗菌药物的使用品种、用药频度、用药合理性进行调查分析。结果抗菌药物使用率为100.0%,共涉及9类29种抗菌药物,用药频率最高的是头孢菌素类,其次是喹诺酮类、青霉素类;用药频度(DDDs)居前3位的抗菌药物分别为头孢呋辛、左氧氟沙星注射液和五水头孢唑林。结论呼吸内科抗菌药物使用基本合理,但仍存在抗菌药物更换频繁、使用时间长、重复用药等问题。

OBJECTIVE To study the antibiotics usage in inpatients in our hospital and guide rational usage of drugs in our hospital. METHODS A total of 224 inpatients with lower respiratory infections from Jan to Oct in 2007 were randomly collected. RESULTS Antibiotics were used in all lower respiratory infections patients and 9 kinds （29 varieties） were used. Cephalosporins were at the first place in use, next were Macrolide and penicillins. Among antibiotics sorted by DDDs, ceftriaxone sodium was the first, next were levofloxacin and cefazolin sodium. CONCLUSIONS The use of antibiotics was safe and effective, but some attentions should be paid to solve the problems of antibiotics usage in respiratory department including drug changed too more frequentIy, long usage time and repeated drug usage.