老干部病房医院获得性肺炎常见病原菌及其耐药性分析

Commonly Encountered Pathogens and Antibiotic Resistance of Hospital Acquired Pneumonia in Cadre Ward

目的了解老干部病房医院获得性肺炎(HAP)常见病原菌及其耐药性。方法对医院老干部病房2005年1月-2007年12月HAP患者痰标本中分离出的病原菌及其耐药性进行回顾性分析。结果共分离出174株病原菌,前5种病原菌分别为铜绿假单胞菌(17.82%)、肺炎克雷伯菌(14.94%)、金黄色葡萄球菌(13.22%)、鲍氏不动杆菌(9.20%)和白色假丝酵母菌(8.62%);革兰阴性杆菌和革兰阳性球菌普遍呈现多药耐药性。结论综合性医院老干部病房HAP发病率高,病原菌以革兰阴性菌为主,常呈多药耐药,及时掌握HAP的常见病原菌及药敏情况,有助于临床合理选用抗菌药物。

OBJECTIVE To study characteristics and drug resistance of the pathogens of hospital acquired pneumonia （HAP） in cadre ward. METHODS Retrospectively analyzed the commonly encountered pathogens and their antibiotic resistance of HAP in cadre ward from Jan 2005 to Dec 2007. RESULTS A total of 174 strains bacteria were isolated. The top five pathogens were Pseudornonas aeruginosa （17.82 %）, Klebsiella pneurnoniae （ 14.94 % ）, Staphylococcus aureus （ 13.22 % ）, Acinetobacter baumannii （9.20 % ） and Candida albicans （8.62 % ）. Both Gram-negative bacteria and Gram-positive cocci were multiple drug-resistant. CONCLUSIONS The incidence of HAP in cadre ward is high and Gram-negative bacteria are the main pathogens. The strains isolated are multiple drug-resistant. It is important to study the characteristics and drug resistance of the pathogens.