摘要
目的分析临床分离的铜绿假单胞菌(PAE)的耐药性,为PAE感染的临床治疗提供依据。方法回顾性调查医院2005年6月-2007年12月PAE感染情况,对分离的286株PAE药敏试验结果进行统计分析。结果PAE对庆大霉素、头孢噻肟、头孢曲松的耐药率均>60.0%;对头孢哌酮/舒巴坦、哌拉西林/他唑巴坦、阿米卡星、左氧氟沙星等抗菌药物尚有较高的敏感率;对碳青酶烯类美罗培南、亚胺培南也产生了17.1%和18.5%的耐药率。结论PAE是医院感染的主要病原菌之一,对其加强耐药性监测,合理应用抗菌药物十分重要。
OBJECTIVE To analyze the resistance of Pseudomonas aeruginosa （PAE） isolated from clinical specimen and provide the guidance for the clinical treatment. METHODS The P. aeruginosas infection status from Jun 2005 to Dec 2007 was reviewed retrospectively, and the results of susceptibility test in 286 strains of PAE were analyzed. RESULTS The drug-resistance rates to gentamicin, cefotaxime, and ceftriaxone in PAE were all above 60.0%, and that to cefoperazone/sulbactam, piperacillin/tazobactam sodium, amikacin and levofloxacin showing all higher sensitivity. The resistance rates to meropenem and imipenem were 17.1% and 18.5%, respectively. CONCLUSIONS P. aeruginosa is one of the main pathogenic bacteria in nosocomial infection. It＇s very important to strengthen the monitoring of drug-resistance of PAE and rationally antibiotics usage.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第4期458-460,共3页
Chinese Journal of Nosocomiology
关键词
铜绿假单胞菌
医院感染
耐药性
监测
Pseudomonas aeruginosa
Nosoeomial infections
Drug-resistance
Monitoring
