乳腺乳头状癌

Papillary Garcinoma of the Breast

1978～1994年间天津肿瘤医院共收治乳腺癌7630例，其中乳腺乳头状癌81例，占同期乳腺癌的1．1％，本病无论临床或病理组织学表现，均具有不同于一般乳腺癌的特点，好发于老年女性，病程长，肿块较大，59例呈囊性，常合并乳头溢液，病理组织学检查，36例为非浸润性癌，20例为早期浸润癌，25例为浸润性癌，腋下淋巴结转移率21．7％。冰冻切片检查尤其囊内型癌易被误诊为良性，应注意鉴别。经手术与化疗综合治疗，5年无瘤生存率89．3％（50／56），10年无瘤生存率为80％（32／40）。

From 1978 to 1994, 7630 cases of breast cancer were admitted in Tianjin Cancer Institute and Hospital, among which 81 cases of papillary carcinoma were diagnosed. Papillary carcinoma had its own characteristic which was different from other breast cancers in clinical and pathological features. It were noticed that the older age of the patients,the prolonged duration of symptoms prior to the surgery, larger tumor size, usually presenting nipple discharge and most of the lesions were cystic. Among them 36 cases were non-invasive breast cancer, 20 cases were early invasive breast cancer and 25 cases were invasive breast cancer respectively. Axillary lymph node metastasis was observed in 16 cases (21.7%). The differential diagnosis between benign papillary tumor and papillary carcinoma, especially intracystic papillary carcinoma was sometime difficult in frozen sections.The prognosis of papilllary carcinoma was good, which the 5—year disease—free survival rate was 89.3% and that of 10-year was 80%.