四氢香叶醇的酯类衍生物合成及其透皮促进作用

Synthesis and Penetration of Tetrahydrogeraniol Derivatives

以四氢香叶醇（３，７－二甲基－１－辛醇）为原料，经酯化、相转移催化反应合成了丙酸四氢香叶醇酯及四氢香叶基硫烷基乙酸乙酯。

Two derivatives were prepared from tetrahydrogeraniol via esterification and PCT reaction respectively They are 3,7dimethyloctyl propionate, ethyl3,7dimethyloctylthioacetateWe evaluated them as penetration enhancer toward 5flourouracil