三羟甲基乙烷催化合成的工艺改进

The technological improvement on catalytic synthesis of trimethylolethane

The synthesis of trimethylolethane using formaldehyde and propionaldehyde as material and a mixed solution of calcium hydroxide and a little triethylamine as catalyst is studied.The effects of the amount of calcium hydroxide,triethylamine,the ratio of reactants,reaction temperature and time are investigated.The optimum conditions are:the molar ratio of formaldehyde to propionaldehyde is 4.0∶1.0;calcium hydroxide to propionaldehyde is 1.2∶1.0;triethylamine to total material(formaldehyde and propionaldehyde) is 0.045∶1.0;temperature of condensation reaction is 25℃;condensation reaction time is 1.0 hour;temperature of Cannizzaro reaction is 35℃;Cannizzaro reaction time is 3.0 hours.The yield of trimethylolethane is 90.4%(based on propionaldehyde).Triethylamine can be recovered for reuse.

The synthesis of trimethyldethane using formaldehyde and propionaldehyde as material and a mixed solution of calcium hydroxide and a little triethylamine as catalyst is studied. The effeets of the amount of calcium hydroxide,triethylamine,the ratio of reactants, reaction temperature and time are investigated. The optimum conditions are： the molar ratio of formaldehyde to propionaldehyde is 4.0： 1.0;calcium hydroxide to propionaldehyde is 1.2： 1.0;triethylamine to total material （formaldehyde and propionaldehyde） is 0.045：1.0 ;temperature of condensation reaction is 25℃;condensation reaction time is 1.0 hour; temperature of Cannizzaro reaction is 35℃; Cannizzaro reaction time is 3.0 hours. The yield of trimethylolethane is 90. 4% （ based on propionaldehyde）. Triethylamine can be recovered for reuse.