摘要
为了观察膀胱癌患者红细胞免疫功能的变化状况，对41例膀胱癌患者（观察组）红细胞免疫功能和血清循环免疫复合物进行检测，并且与55例健康对照组进行比较。结果观察组红细胞C3b受体花环率（RCR）明显低于健康对照组，而红细胞免疫复合物花环率（RCIR）明显增高，血清循环免疫复合物（CIC）含量亦明显高于健康对照组（均P＜0．01）。T1－2期膀胱癌患者RCR水平低于T3－4期膀胱癌患者，而RICR水平则明显高于T3－4期膀胱瘤患者（P＜0．01），CIC含量相应增高（P＜0．05）。膀胱肿瘤切除后RIR升高，RICR降低（P＜0．01）。膀胱癌术后无复发者RCR和RLCR水平及CIC含量与健康对照组无显著性差异（均P＞0．05）；复发者RCR水平明显低于无复发者和健康对照组，而RCIR水平和CIC含量则明显高于无复发者和健康对照组（均P＜0．01）。提示膀胱癌患者红细胞免疫功能降低，血清CIC含量增加；随着肿瘤负荷的减少，机体红细胞免疫功能可逐渐恢复。认为检测膀胱癌患者红细胞免疫功能对疾病诊断、病情估计和预后判断具有一定的意义。
The function of erythrocyte immnity in 41 cases of bladder cancer was detectedThe results showed that the function of erythrocyte immunity in the patients with bladder cancerwas low and the consentration of serum circulating immune complexes (CIC) was significantlyhigher than that in controls. The function of erythrocyte immunity in high stage(T3~4) was lowerthan that of low stage(T1~2),and the consentration of CIC was high in high stage. The function oferythrocyte irnmunity could be enhanced after resection tumor. The function of erythrocyte immunity in patients with recurrence and rnatastasis after tumor removal was low too. This results indicated that monitoring the function of erYthrocyte immunity in patients with bladder cancer wasbenificial to diagnosis,deseases activity evaluation and prognosis.
出处
《临床泌尿外科杂志》
1998年第1期28-31,共4页
Journal of Clinical Urology
