山东省费县秋冬型恙虫病疫源地宿主动物调查研究

Studies of Hosts and Isolation of Rickettsiae tsutsugamushi(Rt)in Natural Focus of Autumn-Winter Type Scrub Typhus in Fei County,Shandong Province

目的：搞清山东省费县地区秋冬型恙虫病疫源地宿主动物种类及其携带恙虫病立克次体（Rt）情况。方法：采用生态学方法确定当地优势鼠种；采用病原分离方法和间接免疫荧光法（IFA）证实鼠类自然感染Rt。结果：1995年5月～1997年4月从野外农田共捕获鼠及鼠形动物1044只，其中黑线姬鼠751只，占71．94％；大仓鼠266只，占25：48％；其它鼠种27只，占2．59％；从室内捕鼠23只，均为褐家鼠。从鼠内脏共分离到9株Rt，其中黑线姬鼠5株，大仓鼠3株，褐家鼠1株，血清学分型：除从黑线姬鼠和大仓鼠各分离到1株Karp型Rt外，其余7株均为Gllliam型。共收集鼠血清318份，抗RtIgG阳性率为14．78％（47／318），血清型以Gilliam型为主，但存在Karp及Kato型。结论：黑线姬鼠为当地秋冬型恙虫病疫源地主要宿主，大仓鼠为次要宿主；褐家既为室内Rt宿主。

In order to find out the hosts of Rt in natural focus of autumn-winter type scrub typhus in Fei county,Shandong province. METHODS:The author carried out a series of studies by isolation of Rt from rodents and IFA to prove the natural infection of rodents. RESULTS: 1044 wild rodents and murine-like animals were captured: 751 were Apodemus agrarius, 266 were Cricetulus triton, one was Cricetulus barabensis, 12 were Crocidura suaveolens, 11 were Rattus norvegicus, 3 were Mus musculus. 9 strains of Rt were isolated from rodents: 5 strains from Apodemus agrarius, 3 strains from Cricetulus triton, one strain from Rattus norvegicus. Serotype revealed that 7 strains of Rt isolated were identical to strain Gilliam while 2 strains from Apodemus agrarius and Cricetulus triton respectively were identical to strain Karp. CONCLUSION:The results of this article indicated that Apodemus agrarius was the most important host of Rt in this focus while Cricetulus triton was more important host;Rattus norvegicus was the host of indoor scrub typhus.