期刊文献+

Polyvinyl Alcohol-Collagen Composite with Glycosaminoglycan as Scaffolds for Tissue Engineering

Polyvinyl Alcohol-Collagen Composite with Glycosaminoglycan as Scaffolds for Tissue Engineering
下载PDF
导出
摘要 The aim of this study is to prepare a PVA-GAG-COL composite material by polyvinyl alcohol (PVA),glycosaminoglycan (GAG) and collagen (COL),and to investigate the feasibility of serving as a scaffold for tissue engineering. PVA was blended with various amounts of GAG and COL. Different proportional scaffolds could be obtained with different molecular weight and alcoholysis degree of PVA and different amounts of GAG,which exhibited high water content (60%-95%) and showed different inner configuration with swelling ratio (120%-620%). SEM proved that different composite materials had different porous structures. The aim of this study is to prepare a PVA-GAG-COL composite material by polyvinyl alcohol ( PVA), glycosaminoglycan (GAG) and collagen (COL) ,and to investigate the feasibility of serving as a scaffold for tissue engineering. PVA was blended with various amounts of GAG and COL. Different proportional scaffolds could be obtained with different molecular weight and alcoholysis degree of PVA and different amounts of GAG, which exhibited high water content (60% -95% ) and showed different inner configuration with swelling ratio ( 120% - 620% ). SEM proved that different composite materials had different porous structures.
出处 《Chinese Journal of Biomedical Engineering(English Edition)》 2008年第4期166-176,共11页 中国生物医学工程学报(英文版)
基金 National Nature Foundation grant number:30371519
关键词 polyvinyl alcohol GLYCOSAMINOGLYCAN COLLAGEN SCAFFOLD tissue engineering 聚乙烯乙醇 糖胺聚糖 胶原蛋白 组织工程
  • 相关文献

参考文献10

  • 1Harley BAC,Gibson LJ.In vivo and in vitro applications of collagen-GAG scaffolds[].Chemical Engineering.2008
  • 2Kim SJ,Yoon SG,Lee M, et al.Electrical behavior of polymer hydrogel composed of poly(vinyl alcohol)-hyalu- ronic acid in solution[].Biosensors and Bioelectronics.2004
  • 3Nebahat Degirmenbasi,Dilhan M Kalyon,Elvan Birinci.Biocomposites of nanohydroxyapatite with collagen and poly(vinyl alcohol)[].Colloids and Surfaces.2006
  • 4Lee CT,Kung PH,Lee YD.Preparation of poly(vinyl alcohol)-chondroitin sulfate hydrogel as matrices in tissue engineering[].Carbohydrate Polymers.2005
  • 5Brendan A,Janet H.Leungb,Emilio C.et al.Mechanical characterizationof collagen glycosaminoglycan scaffolds[].Gibsonb Acta Biomaterialia.2007
  • 6O Brien FJ,Harley BA,Yannas IV,et al.The effect ofpore size on cell adhesion in collagen-GAG scaffolds[].Biomaterials.2005
  • 7Duan X,McLaughlin C,Griffith M,Sheardown H.Biofunctionalization of collagen for improved biological response: scaffolds for corneal tissue engineering[].Biomaterials.2007
  • 8Jiansu Chen , Qinhua Li &#8224,</a> , Jintang Xu , Yaoxiong Huang &#8224,</a> , Yong Ding , Hongwei Deng &#8225,</a> , Songbin Zhao , and Rui Chen <.Study on Biocompatibility of Complexes of Collagen-Chitosan-Sodium Hyaluronate and Cornea[].Artificial Organs.2005
  • 9Kobayashi H,,Kato M, et al.Collagen immobilized PVA hydrogcl-hydroxyapatite composites prepared by kneading methods as a material for peripheral cuff of artificial cornea[].Journal of Materials Science.2004
  • 10Nuttelman CR,Henry SM,Anseth KS.Synthesis and characterization of photocrosslinkable, degradable poly(vinyl alcohol)-based tissue engineering scaffolds[].Biomaterials.2002

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部