摘要
The aim of this study is to prepare a PVA-GAG-COL composite material by polyvinyl alcohol (PVA),glycosaminoglycan (GAG) and collagen (COL),and to investigate the feasibility of serving as a scaffold for tissue engineering. PVA was blended with various amounts of GAG and COL. Different proportional scaffolds could be obtained with different molecular weight and alcoholysis degree of PVA and different amounts of GAG,which exhibited high water content (60%-95%) and showed different inner configuration with swelling ratio (120%-620%). SEM proved that different composite materials had different porous structures.
The aim of this study is to prepare a PVA-GAG-COL composite material by polyvinyl alcohol ( PVA), glycosaminoglycan (GAG) and collagen (COL) ,and to investigate the feasibility of serving as a scaffold for tissue engineering. PVA was blended with various amounts of GAG and COL. Different proportional scaffolds could be obtained with different molecular weight and alcoholysis degree of PVA and different amounts of GAG, which exhibited high water content (60% -95% ) and showed different inner configuration with swelling ratio ( 120% - 620% ). SEM proved that different composite materials had different porous structures.
基金
National Nature Foundation
grant number:30371519