三拗汤及其组方药材挥发性成分比较分析

Comparative Analysis of the Volatile Components from Oils of San-ao Decoction and its Major Constituing Herbs by GC-MS

目的:探讨三拗汤各组方药材组成复方后挥发油的组成成分变化。方法:采用水蒸汽蒸馏法提取三拗汤及其富含挥发油的组方药材麻黄、苦杏仁的挥发油,并通过GC-MS联用技术对其进行分析鉴定和比较研究。结果:三拗汤挥发油的GC-MS TIC化学信号主要来源于组方药材麻黄和苦杏仁,但是单味药材麻黄和苦杏仁中一些化学信号于复方三拗汤中未检测到。结论:利用GC-MS比较分析方法研究三拗汤各组方药材组成复方后挥发性成分的变化,为揭示其效应物质基础和配伍机理奠定基础。

Objective：To evaluate the correlativity between volatile components of San-ao Decoction and its major constituting herbs. Methods： The chemical compositions of essential oils, obtained by hydrodistillation from San-ao Decoction and its major constituting herbs （Herba Ephedrae and Semen Armeniacae Amarum. ）, were analyzed by GC- MS. Results： The volatile components of San-ao Decoction were mostly derived from Herba Ephedrae and Semen Armeniacae Amarum. Conclusion： The method of GC-MS appears to bethe potential method to analyze the bioactive components of TCM and TCM formulae.