糖化血红蛋白和糖耐量试验在妊娠期糖尿病中的临床意义

Clinical signification of HbA1c and oral glucose tolerance in patients with gestational diabetes mellitus

目的:探讨糖化血红蛋白及糖耐量试验在妊娠期糖尿病中的临床意义。方法:采用回顾性分析方法,对2006年1月至2007年12月确诊为GDM在本院住院并进行了治疗的患者共61例进行资料分析。其中单纯饮食控制44例(组1),饮食控制加胰岛素治疗17例(组2),均理想的控制了血糖并给予积极的随访。结果:组1和组2的治疗前空腹血糖,餐后1、2 h血糖、糖化血红蛋白差异有显著性。P<0.05。餐后3 h血糖无显著性差异。结论:糖化血红蛋白及糖耐量试验能预测妊娠期糖尿病的期别,对治疗有指导意义。

Objective：To investigate the clinical signification of HbA1 c and 75 g oral glucose tolerance test （OGTT） in patients with gestational diabetes mellitus （ GDM ）. Methods ： Use the methods of review and analysis to conduct the data analysis on 61 patients who were diagnosed to be GDM and admitted and treated in the hospital during the period from January 2006 to December 2007.44 cases were treated with simple dietetic control （ group 1 ）. 17 cases were treated with both dietetic control and use of Insulin （group 2）. All patients＇ plasma glucose was controlled perfectly. At the same time, Follow-up was conducted to these 61 patients. Results：There were significant differences of fasting plasma glucose, 1 hr plasma glucose, 2hr plasma glucose and HbAI c before treatment between group 1 and group 2 （ P 〈 0. 05 ）. There were no significant differences of 3hr plasma glucose between these two groups. Conclusion：The tests of HbA1 c, OGTF can forecast the degrees of GDM and play some directive roles in treatment.