摘要
线粒体基因是独立于核基因外的遗传物质,其独特的结构功能、遗传特性以及与个体胰岛素抵抗之间的相关性,可能与导致生育期妇女不孕的多囊卵巢综合征相关联,从而有可能为多囊卵巢综合征复杂病因和发病机制的研究开辟一条新途径,为临床诊治提供新的思路。
Mitochondrial DNA, independent of nuclear DNA, is probably associated with polycystic ovary syndrome (PCOS), owing to its unique structure, special function, hereditary characteristics, and relationship with insulin resistant. The investigation on mitochondrial DNA might be a new way for the study of the etiology and pathogenesis of PCOS, and provide a new approach to the diagnosis and therapy for the patients with PCOS.
出处
《生殖医学杂志》
CAS
2009年第1期67-70,共4页
Journal of Reproductive Medicine
基金
教育部留学回国人员科研启动基金
关键词
线粒体基因突变
胰岛素抵抗
卵泡发育
卵母细胞凋亡
多囊卵巢综合征
Mitochondrial DNA mutation
Insulin resistant
Ovarian development
Oocyte apoptosis
Polycystic ovary syndrome