双源CT不同R-R间期间隔法在定量评估左心功能中的对比研究

Comparison with Reconstructions of Different R-R Interval in Assessment of Left Ventricular Function Using Dual-Source CT

目的探讨双源CT(dual-source CT,DSCT)不同R-R间期间隔重组在测定评估左心功能时有无差异性。资料与方法对正常组(24名)和冠心病患者组(26例)行DSCT冠状动脉造影,分别以2%、5%及10%R-R间期间隔重组,并测定各间期左室舒张末期容积(EDV)、收缩末期容积(ESV)、每搏输出量(SV)、左室射血分数(EF)。对测得的数据行单因素方差分析。结果以2%、5%及10%R-R间期间隔重组测定左心功能时,各参数间差异无显著统计学意义。结论以2%、5%及10%R-R间期间隔重组测定左心功能各指标之间的相关性高,临床可以应用10%R-R间期间隔重组测定左心功能,相对方便、快捷、精确。

Objective To evaluate the differences of the left ventricular （LV） function by using the data sets reconstructed every 2% ,5% and 10% （0 - 100% ） of the R-R interval. Materials and Methods Twenty-four heahhy adults （ 18 males,6 females） and twenty-six patients with known coronary artery disease （CAD） referred to our department for noninvasive dual-source CT coronary angiography （DSCTA）were included in this study. To evaluate LV function ,0.75 mm slices were reconstructed in the short-axis orientation,starting at 0% to 100% of cardiac cycle in various interval of 2% ,5% and 10%,respectively. LV end-diastolic volume（LVEDV） and LV end-systolic volume （LVESV） were determined and the LV ejection fraction（LVEF） was derived. Results No significant differences were found when comparing the reconstructions among the measurements of every 2% ,5% and 10% of the R-R interval. Conclusion Excellent correlations between reconstruction of 2% ,5% and 10% of the R-R interval were shown for the assessment of LV function and LV volume.