超重肥胖对血糖和血脂水平的影响

The effect of overweight and obesity on fasting serum glucose and serum lipid

目的：探讨超重与肥胖对血糖和血脂水平的影响,为心血管病、糖尿病的防治提供科学依据。方法：测量咸宁市农村1641例居民的身高、体重、腰围和臀围,采集空腹静脉血测定血糖（FSG）、血清总胆固醇（TC）,甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）,用Fried-wald’s公式计算低密度脂蛋白胆固醇（LDL-C）。对超重肥胖组和体重正常组血糖、血脂进行比较。结果：超重肥胖率为20.78%,超重肥胖组FSG、TG及LDL-C水平高于体重正常组,而HDL-C水平低于体重正常组;超重肥胖组FSG、TG及HDL-C异常检出率也高于体重正常组;相关分析显示,体质指数（BMI）、腰臀比（WHR）与FSG、TC、TG呈正相关,WHR与HDL-C呈负相关。

Objective： To explore the effect of overweight and obesity on fasting serum glucose （FSG） and serum lipid, and to provide scientific evidence for prevention of cardiovascular disease and diabetes meUitus. Methods： A multistage survey for 1641 people in rural area in Xianning city Hubei province was performed. Their height, weight, waist circumference, hip circumference were measured,and their FSG, TC, TG, HDL - C were also determined with the fasting blood sample. LDL - C was calculated based on Friedwald formula. FSG and serum lipid in the overweight and obesity group were compared with normal weight group. Results： The prevalence rate of overweight and obesity was 20.78%. Overweight and obesity group had FSG, TG and lower HDL - C as compared with normal weight group. The prevalence of higher TG, higher FSG and lower HDL - C in the overweight and obesity group was significantly higher than in normal weight group. Correlation analysis showed that body mass index （BMI）, WHR were positive correlation with FSG, TC, TG, and WHR was negative eorrelation with HDL- C. Conclusion： Overweight and obesity are correlated to FSG and serum lipid. Overweight and obesity showed be controlled.