英连金和胃方治疗胃癌前病变53例临床观察

Clinical observation of Yinglianjinhewei prescription on precancerous lesions of gastric cancer

目的观察英连金和胃方治疗胃癌前病变的临床疗效。方法将105例患者随机分为2组。治疗组53例予英连金和胃方,每次1袋,每日3次口服;对照组52例予胃复春片,每次4片,每日3次口服。治疗前后详细记录临床症状、胃镜下黏膜及病理改变情况。结果治疗组总有效率84.9%,对照组总有效率63.5%,2组比较差异有统计学意义(P<0.05),治疗组疗效优于对照组;2组治疗前后胃镜疗效改善率比较差异有统计学意义(P<0.01,P<0.05),治疗组优于对照组;2组病理疗效治愈率比较差异有统计学意义(P<0.01,P<0.05),治疗组优于对照组。结论英连金和胃方治疗胃癌前病变有显著疗效。

Objective To observe the effect of Yinglianjinhewei prescription on precancerous lesions of gastric cancer. Methods 105 patients were randomly divided into two groups. Patients in control group （ n = 52） were treated by Weifuchun, 4 pills, thrice a day. Patients in treatment group （ n = 53） were treated by Yinglianjinhewei prescription, a sack, thrice a day. Clinical symptoms, mucosal and pathological changes under gastroscope were recorded. Results The total effective rate in treatment group （84.9 % ） was higher than that in control group （63.5 %, P 〈 0.05）. There was sig- nificant difference between before and after treatment in two groups on improvement rate of gastroscope effect （ P 〈 0.01, P 〈 0.05） . Improvement rate of gastroscope efihct in treatment group was superior to that in control group. Conclusion Yinglianjinhewei prescription has significant effect on precancerous lesions of gastric cancer.