摘要
为颅脑手术病人寻求过渡通气时较为理想的潮气量,采用不同潮气量(12mL/kg、10mL/kg、8mL/kg)对三组颅脑手术病人实行过度通气,观察其对颅脑手术病人脑氧代谢的影响。结果显示:Ⅰ组动脉血二氧化碳分压(PaCO2)、颈内静脉氧分压(PjvO2)和颈内静脉二氧化碳分压(PjvCO2)较基础值和Ⅱ、Ⅲ二组对应值低(P〈0.01);通气60min后Ⅰ组颈内静脉血氧饱和度(SjvO2)、颈内静脉血氧含量(CjvO2)降低,而脑氧摄取(CEO2)增高,与其基础值及Ⅱ、Ⅲ组的对应值相比较,差异有统计学意义(P〈0.05);重度过度通气的Ⅰ组,有40%(4/10)的病人其SjvO2〈50%。结论:维持潮气量为8-10mL/kg,是颅脑手术病人较为理想的过度通气。
To find a better hyperventilation for patients with craniocerebral operations. Method Three groups of patients undergoing craniocerebral operations were hyperventilated with different tidal volume( 12mL/kg, 10mL/kg, 8mL/kg), to observe the effect of various degrees of tidal volume on the cerebral O2 metabolism in patients with craniocerebral operations. It is demonstrated that the PaCO2, PjvO2 and PjvCO2 in group Ⅰ were lower than the baselines and that of group Ⅱ and group Ⅲ( P 〈 0.01 ). After 60 minutes of ventilation, the SjvO2 and CjvO2 decreased, and CEO2 increased in group Ⅰ, which were statistically significant compared with the baselines and that of group Ⅱ and group Ⅲ( P 〈 0.05). In group I, the SjvO2 of 40% patients is less than 50%. It is concluded that deep hyperventilation(the tidal volume at 12mL/kg) leads to disorders of cerebral O2 metabolism and the tidal volume at 8 - 10mL/kg is the better hyperventilation for patients with eraniocerebral operations.
出处
《石河子大学学报(自然科学版)》
CAS
2008年第6期732-734,共3页
Journal of Shihezi University(Natural Science)
关键词
过度通气
潮气量
脑氧代谢
颅脑手术
hyperventilation
tidal volume
cerebral O2 metabolism
craniocerebral operation