慢性疾病患者服药依从性测量量表的编制

Development of a Medication Compliance Scale in Patients with Chronic Diseases

目的编制适合我国慢性疾病患者服药依从性测量量表。方法根据我国普遍认同的依从性的涵义及国内外相关文献构建量表结构。并据此形成量表条目池。采用条目答案分布法等5种方法进行条目筛选,最后保留16条条目形成量表初稿,对其进行信度和效度的考评。结果因子分析提取的公因子能较好地获得专业解释,量表结构与理论构想基本一致。与患者自评的会聚效度为0.55～0.59;与Morisky问卷效标的相关系数为0.58。Cronbaeh α系数、β系数和Ω系数分别为0.717,0.751,0.893;重测信度为0.95。结论初步建立的慢性疾病患者服药依从性测量量表各考评指标能达到量表的一般要求,可试用于依从性的测量,并在此过程中作进一步的完善。

Objective To develop a reliable scale for evaluating medication compliance among patients with chronic diseases in China. Methods An initial item pool was generated by literature review, based on the definition of compliance generally accepted in China. The items were then subjected to item selections by using item answer distribution and other four methods, which resulted in a primary scale with 16 items. The reliability and validity of this scale was examined. Results Common factors extracted by factor analysis were well explained, there being a close correspondence between the scale construction and the theoretical construction. Convergent validity with the patients＇ self-ratings on medication compliance ranged from 0.55 to 0.59, and the correlation coefficient with the score of Morisky questionnaire was 0.58. The Cronbach α, θ and Ω coefficients were 0.717, 0.751, 0.893 respectively, and test-retest reliability was 0.95. Conclusion The newly developed scale appears reliable and may be a useful tool for measuring drug compliance among patients with chronic diseases, but there are still areas where further improvements may be needed.