依据“患者自评表”制定PMS肝气逆证疗效评价参考标准的研究

PMS Criterion of Therapeutical Evaluation of Adverse Liverqi Syndrome According to Self-evaluation Scale for Patients

目的:针对临床缺乏经前期综合征(PMS)肝气逆证疗效评价标准的情况,建立PMS肝气逆证疗效评价参考标准。方法:采用随机双盲对照多中心的原则,依据"PMS肝气逆证症状严重程度患者自评表"初步建立PMS肝气逆证疗效评价参考标准。结果:"经前平颗粒"和安慰剂对于PMS肝气逆证患者均具有治疗效果,经前平组疗效明显优于安慰剂组;"患者自评表"可以作为疗效评价指标。结论:初步建立PMS肝气逆证疗效评价参考标准,为PMS肝气逆证疗效评价行业标准的建立提供了参考。

Objective： To establish PMS criterion of therapeutical evaluation of adverse liver-qi syndrome. Methods： The multicentered, randomized double-blind principle was used to establish the PMS criterion of therapeutical evaluation of adverse liverqi syndrome according to Self-ewaluation Scale of Severity of Adverse Liver-qi Syndrome for Patients. Results： Jingqianping Granule and placebo have the therapeutic effect on adverse liver-qi syndrome; the therapeutic effect of Jingqianping Granule was better than that of placebo. Self-evaluation Scale of Severity of Adverse Liver qi Syndrome for Patients can be used as the evaluation index for the therapeutic effect. Conclusion： The elementary establishment of PMS criterion of therapeutical evaluation of adverse liver-qi syndrome offers an important basis for the establishment of professional PMS criterion of therapeutical evaluation of adverse liver-qi syndrome.