沧州市人群弓形虫感染血清流行病学调查

Serological Survey of Antibodies IgG and IgM to Toxoplasma among Population of Cangzhou City

目的了解沧州市人群弓形虫感染现状。方法于2007年1—5月在沧州某医院留取门诊血清和医务人员血清共637份,采用ELISA方法检测血清弓形虫IgG、IgM抗体。结果共检测637人,总阳性率为6.3%,IgG阳性率为5.2%,IgM阳性率为1.1%。19～24岁和49～60岁年龄段的人群感染率较高。居住农村、文化程度低、务农、做饭时生熟食刀具、砧板不分以及切完生肉后没有洗手习惯的人群阳性率较高(P<0.05)。结论本次调查人群存在弓形虫感染,阳性率与年龄、文化程度、职业、居住地、卫生饮食习惯有关。

Objective The aim of this research was to provide a basis for the development of preventive and curative measures against the toxoplasma infection by investigating the current infection of toxoplasma and its epidemic characteristics among the population of the Cangzhou city. Methods Antibodies IgG and IgM against toxoplasma in the sera were determined by ELISA during Jan.-May,2007. Results Six hundred and thirty-servn subjects were screened. The positive rate was 6.3% for total antibodies, 5.2% for IgG and 1.1% for IgM. The infection rate was higher in the population aged 19-24 years and 49-60 years.The positive rate was higher in farmers living in countryside, those who were poor educated and who had bad habit of cooking food without separating knives and chopping boards to handle raw food and ready-to-eat food and washing their hands after cutting raw meat （P〈0.05）. Conclusion The serological positive rate in this data was 6.3%, related to age, educational background, occupation, residence and unsanitary cooking habits. Therefore, it is necessary to provide health education with preventive knowledge of the toxoplasma infection by getting out of those unsanitary habits.