摘要
用CA15I-3RIA测定了41例术前乳腺肿瘤和113例乳腺癌术后患者的血清。其中,术前25例为乳腺癌,其灵敏度为20.0%,特异性为93.7%;59例诊断为乳腺癌术后复发者,灵敏度为71.2%。50例诊断为骨转移者,灵敏度为78.0%.结果表明:由于CA15-3对早期乳腺癌的灵敏度较低,不适于作乳腺癌普查。但是,它对于乳腺癌术后复发、转移,尤其是对骨等脏器的转移具有较高的诊断价值。
Serum CA15-3 levels of 41 pre-operative patients with breast tumor and 113post-operative patients with breast cancer were meassured by radioimmunoassay.The sensitivity and specificity were 20%, 93.7%, and 71.2%, respectively. In 50patients with bone metastasis, the sensitivity was 78.0%. It appears that due to itslow sensitivity for early diagnosis, CA15-3 RIA has little use for screening in generalpopulation to detect primary breast cancer in early stage but is benefical fordetecting its metastasis and recurrence.
出处
《核技术》
CAS
CSCD
北大核心
1998年第5期307-309,共3页
Nuclear Techniques