抗菌肽在转基因动植物中的研究进展

Progress of Antibacterial Peptides in Transgenic Plants and Animals

抗菌肽是一类广泛存在于生物界的小分子短肽,具有广谱的抗菌、抗病毒、抗寄生虫及抗癌等生物活性。将抗菌肽基因转入动、植物体内,不仅可以提高动、植物的抗病能力,而且有望通过转基因动、植物来大量生产抗菌肽,具有重要的研究价值和广阔的应用前景。就抗菌肽的特性、抗菌机理及其在转基因动、植物中的研究做一简要的综述。

Antibacterial peptides,a family of short-chain peptides,are widely spread in biological world. Besides broad-spectrum antibacterial activity,antibacterial peptides have biological activities on the resistance of virus,parasite and tumor. Transgenic plants and animals transformed with genes of antibacterial peptides could enhance disease-resistant activity. In this paper,the characteristics,application and progress of antibacterial peptides in transgenic plant and animal were summarized.