α-亚麻酸多重乳液的稳定性研究

Study on Stability of α-Linolenic Acid Multiple Emulsion

目的制备较为稳定的α-亚麻酸多重乳液。方法以多重乳液相对体积为衡量标准,用显微镜直接观察,分别探讨第一相中复合乳化剂亲水-亲油平衡(HLB)值以及复合乳化剂质量分数对α-亚麻酸W/O/W多重乳液稳定性的影响。用紫外分光光度法测定α-亚麻酸在多重乳液中的稳定性。结果第一相复合乳化剂HLB值为6.6,M(复合乳化剂)∶M(EL35)=5.6,乳化剂在多重乳液中的质量分数为9.9%时,多重乳液相对体积最大,α-亚麻酸在多重乳液中的稳定性最好。结论制备了较稳定的α-亚麻酸多重乳液。

Objective To prepare stable α -linolenic acid multiple emulsion. Methods With relative volume percentages as measurement data, the effects of HLB value and concentration of complex emulsifier in the first phase on the stability of α -linolenic acid multiple emulsion （W/O/W） were examined by microscopic observation. The stability of α-linolenic acid in multiple emulsion was measured by ultraviolet spectrophotometry. Results The optimum conditions for complex emulsifier system were as follows： the HLB value of complex emulsifier in the first phase was 6.6; the ratio of M （complex emulsifier） to M （EL35） was 5.6; the mass fraction of emulsifiers in multiple emulsion was 9.9 %. Under the conditions mentioned above, the relative volume percentage of multiple emulsion was the biggest and the stability of α-linolenic acid was the best. Conclusion α-Linolenic acid multiple emulsion can be prepared with better stability.