丹参注射液对糖尿病患者血液流变学的影响

Effect of Salvia Injection on Hemorheology of Diabetic Patients

[目的]观察丹参注射液对糖尿病患者液流变学的影响。[方法]65例糖尿病患者随机分为两组,治疗组33例在对照组基础上给予丹参注射液40ml/d,治疗前后分别检测两组患者血液流变学参数。[结果]对照组治疗后血浆黏度、纤维蛋白原、红细胞聚集指数、红细胞变形指数明显改善(P<0.05)。治疗组治疗后血液流变学各项检测指标较治疗前显著改善(P<0.01)。两组比较全血高切黏度、低切黏度降低有统计学意义(P<0.05),血浆黏度、红细胞变形指数、红细胞聚集指数改善有显著统计学差异(P<0.01)。[结论]丹参注射液能有效改善糖尿病患者血液流变学异常的作用。

[Objective]To observe the effect of Salvia Injection on the hemorheology of diabetic patients. [Method] Randomly divide 65 cases into 2 groups,the treatment group 33 cases were administered with Salvia Injection 40 ml/d on the basis of control one. Respectively measure both diameters of hemorheology before and after treatment. [Result] After treatment,for the control group,the plasma mucosity, fibrinogen, red cell aggregation index and deformation index were markedly improved（P〈0.05） ;for the treatment group, all hemorheology indexes were much better than before treatment（P〈0.01 ）. The high-shear and low-shear whole blood viscosity decrease of both groups had statistical difference（P〈0.05）, so were the obvious improvement of plasma viscosity, red cell deformation index and aggregation index （P〈0.01）. [Conclusion] Salvia Injection can effectively improve abnormal hemorheology of diabetic patients.