摘要
目的:探讨黑斑-息肉综合征(Peutz-Jeghers Syndrome,PJS)的临床诊治方法。方法:通过2例PJS病例报告,分析PJS的诊治进展。结果:PJS是一种少见的常染色体显性遗传病,以皮肤黏膜黑色素沉着及胃肠道多发性息肉为特征,其致病基因为19p上的STK 11基因。结论:PJS致病基因与肿瘤的发生和发展密切相关。
Objective： To investigate the clinical diagnosis and treatment of Peutz-Jeghers Syndrome. Methods： Analysis the progress in diagnosis and treatment of PJS by 2 cases report of PJS. Results： PJS is a rare inherited disease with autosomal dominant trait, which is characterized by the presence of mucocutaneous pig- mentation and hamartomatous gastrointestinal polyps, STK 11 on chromosome 19p are responsible for most cases of PJS. Conclusions： The main genes responsible of PJS has close correlation with formation and development of tumors.
出处
《内蒙古医学杂志》
2009年第1期52-54,共3页
Inner Mongolia Medical Journal
