摘要
目的分析受体介导的放射性同位素靶向治疗对多处转移的胰升糖素瘤的疗效。方法讨论1例41岁女性胰升糖素瘤患者术后化疗后采用放射性同位素治疗的疗效。结果患者经^(90)Y-DOTA-奥曲肽治疗后症状基本消失,血清胰升糖素水平基本稳定而腹部CT显示肝转移病灶略有缩小。结论^(90)Y-DOTA-奥曲肽治疗恶性胰升糖素瘤有一定疗效。
Objectives To explore the efficacy of receptor - mediated radionuclide for malignant glucagonama in one case. Methods We report a case of 41-year-old female patient with a 5-year history of recurrent necrolytic migratory erythema, who had been diagnosed as glucagonoma and undergone surgery 1.5-years before. After 6 courses of the chemotherapy, she was still afflicted by necrolytic migratory erythema. The somatostatin LAC was used and the symptoms were relieved, but all of them relapsed while the drug was discontinued. Results The patient accepted the ^90Y-DOTA -octreotate therapy, and all symptoms were relieved and the metastatic tumors were mildly reduced. Conclusion ^90Y-DOTA - octreotate therapy for Chinese patients of glucagonoma is effective.
出处
《癌症进展》
2009年第1期92-95,共4页
Oncology Progress
