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奥扎格雷治疗短暂性脑缺血发作的疗效和安全性

Efficacy and safety of ozagrel in treating transient cerebral ischemic attack
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摘要 目的研究奥扎格雷治疗短暂性脑缺血发作(TIA)的临床效果。方法将符合标准的入选病例分为:治疗组41例,给予奥扎格雷160mg·d-1,分两次静脉滴注;对照组40例,给予阿司匹林150mg·d-1,口服,2组疗程均为14d,并于治疗结束后随访60d。结果2组临床疗效比较,差异有显著意义(P<0.05);治疗组较对照组的基本治愈率明显提高(75%VS50%,P<0.05)。结论奥扎格雷治疗TIA效果确切,可降低TIA病人脑梗死的发生率。 Objective To study the clinical effect of treating transient cerebral ischemic (TIA) with ozagrel.Methods Patients coincided with the selecting standard were divided into a trial group,41patients,treating with ozagrel twice a day, totaling 160mg·d^-1,iv,gtt; and control group,40 patients,giving oral aspirin once a day,totaling 150·mgd-1.The course of treatment for both groups was 14 d for each;with followup survey of 60d.Resuhs There was significant difference between the clinical effects of the two groups (P〈0.05),with the basic cure rate of trial group obviously higher than that of the controlled group (75%vs50%,respectively,P〈0,05).Conelusions Treatment of TIA with ozagrel is definitely effective and may reduce the incidence of cerebral infarction.
作者 刘丽萍
机构地区 通辽市铁路医院
出处 《当代医学》 2009年第3期25-26,共2页 Contemporary Medicine
关键词 奥扎格雷 脑缺血 阿司匹林 ozagrel cerebral ischemia aspirin
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