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胆固醇的跨膜外向转运及调控 被引量:10

The transmembrane extroversion transport and regulation of cholesterol
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摘要 组织细胞胆固醇的外向跨膜转运要有ATP结合盒转运体A1(ABCA1)、ABCG1、B族I型清道夫受体(SR-BI)、载脂蛋白AⅠ(apoAⅠ)/高密度脂蛋白(HDL)等多种膜蛋白的共同参与,并且受过氧化物酶增殖活化受体(PPAR)及肝X受体(LXR)的调控。文中就参与胆固醇跨膜转运过程的膜蛋白与调控因子的结构和功能作一综述。 Membrane proteins such as ABCA1 ,ABCG1 ,SR-BI,apoA Ⅰ / HDL participate in the transmembrane extroversion transport of cholesterol. PPAR, LXR regulate the course, the author summarize the structure and function of the membrane proteins and regulating factors in this article.
出处 《医学研究生学报》 CAS 2009年第2期198-200,204,共4页 Journal of Medical Postgraduates
基金 国家自然科学基金资助项目(批准号:30371566) 河北省自然科学基金资助项目(批准号:303472)
关键词 胆固醇 转运 膜蛋白 调控 Cholesterol Transport Membrane protein Regulation
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参考文献18

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