整合素连接激酶在肿瘤中研究进展
Research on integrin-finked kinase in cancers
摘要
整合素连接激酶（ILK）由于在多种肿瘤中的表达和活性都上调，因而对肿瘤的诊断具有一定价值。抑制ILK的活性可导致细胞周期阻滞和细胞凋亡，从而成为肿瘤基因治疗和肿瘤药物的理想靶点。
Beause integrin-linked kinase （ILK） has increased exression and activity in varieties of tumors, so the diagnosis of tumors has certain significance. Inhibition of ILK activity can lead to cell cycle arrest and apoptosis, thus becoming the ideal target of tumor dgugsand tumor gene therapy.
出处
《国际肿瘤学杂志》
CAS
2009年第2期97-99,共3页
Journal of International Oncology
关键词
基因表达调控
肿瘤
信号传导
整合素连接激酶
Gene expression regulation, neoplastic
Signal transduction
Integrin-linked kinase
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