期刊文献+

甲状腺干细胞及其与甲状腺肿瘤干细胞的关系

Thyroid stem cells and thyroid tumor stem cells
原文传递
导出
摘要 甲状腺干细胞是存在于甲状腺组织内具有自我更新及增殖分化潜能的细胞。甲状腺肿瘤干细胞是甲状腺肿瘤组织中与甲状腺干细胞相似的细胞,是甲状腺肿瘤发生发展的细胞来源。研究表明,甲状腺干细胞是甲状腺肿瘤干细胞的重要来源,其恶变时所处的分化阶段对甲状腺肿瘤的恶性程度有重要影响。 Thyroid stem cells have potential of self-renewing, proliferation and differentiation in thy- roid. Thyroid tumor stem cells similar to thyroid stem cells in thyroid are origin of thyroid tumor cells. Thyroid stem cells are important source of thyroid tumor stem cells and stages of differentiation have important influence on malignancy of thyroid tumor.
出处 《国际肿瘤学杂志》 CAS 2009年第2期121-123,共3页 Journal of International Oncology
关键词 干细胞 肿瘤干细胞 甲状腺肿瘤 Stem cells Neoplastic stem cells Thyroid neoplasms
  • 相关文献

参考文献16

  • 1Preto A, Cameselle-Teijeiro J, Moldes- Boullosa J, et al. Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. Mod Pathol, 2004, 17(7) : 819-826.
  • 2Burstein DE, Nagi C, Wang BY, et al. Immunohistochemical detection of p53 homolog p63 in solid cell nests, papillary thyroid carcinoma, and hashimoto' s thyroiditis : A stem cell hypothesis of papillary carcinoma nncogenesis. Hum Pathol, 2004, 35(4) :465-473.
  • 3Sarosi G, Brown G, Jaiswal K, et al. Bone marrow progenitor cells contribute to esophageal regeneration and metaplasia in a rat model of Barrett's esophagus. Dis Esophagus, 2008, 21 ( 1 ) :43-50.
  • 4Koide Y, Morikawa S, Mabuchi Y, et al. Two distinct stem cell line- ages in murine bone marrow. Stem Cells, 2007, 25(5) :1213-1221.
  • 5Thomas T, Nowka K, Lan L, et al. Expression of endoderm stem cell markers: evidence for the presence of adult stem cells in human thyroid glands. Thyroid, 2006, 16(6) :537-544.
  • 6Lan L, Cui D, Nowka K, et al. Stem cells derived from goiters in a-dults form spheres in response to intense growth stimulation and require thyrotropin for differentiation into thyrocytes. J Clini Endocrinol Metabo, 2007, 92(9):3681-3688.
  • 7Hoshi N, Kusakabe T, Taylor B J, et al. Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics. Endocrinology, 2007, 148(9) :4251-4258.
  • 8Wu C, Alman BA. Side population cells in human cancers. Cancer Lett, 2008, 268(1):1-9.
  • 9Mitsutake N, Iwao A, Nagai K, et al. Characterization of side population in thyroid cancer cell lines. Endocrinology, 2007, 148 ( 4 ) : 1797 - 1803.
  • 10Vasko VV, Saji M. Molecular mechanisms involved in differentiated thyroid cancer invasion and metastasis. Curr Opin Oncol, 2007, 19 (1):11-17.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部