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人类白细胞抗原-G及其与妇科肿瘤的关系

Correlation between human leukocyte antigen G and gynecological neoplasms
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摘要 免疫逃逸在妇科恶性肿瘤发病中的作用日益受到重视。人类白细胞抗原-G（HLA—G）分子是主要组织相容复合物Ⅰ家族中的主要成员，具有抑制免疫的作用，在妇科肿瘤的免疫逃逸中发挥了重要作用。 The immune tolerance or immune escape plays important roles in the genesis and progression of malignant gynecological neoplasms, Human leukocyte antigen G （ HLA- G） is an important member of major histocompatiblity complex class Ⅰ . HLA-G seems to affect almost every aspect of human immunity. It can inhibit immunological function, and play an important role in immune escape of malignant gynecological neoplasms.
作者 韩雪川(综述) 赵兴波(审校)
机构地区 山东大学附属省立医院妇产科
出处 《国际肿瘤学杂志》 CAS 2009年第2期144-146,共3页 Journal of International Oncology
关键词 HLA抗原 组织相容性抗原Ⅰ类 免疫耐受 生殖器肿瘤 女(雌)性 HLA antigens Histocompatibility antigens class Ⅰ Immune tolerance Genital neo- plasm, female
分类号 R392.11 [医药卫生—免疫学] R737.3 [医药卫生—肿瘤]
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国际肿瘤学杂志
2009年 第2期

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