摘要
99Tcm is the most commonly used diagnostic radioisotope.And 188Re is an excellent therapeutic radioisotope with a gamma photon for imaging.Both locate in the same group and have very similar properties. 99Tcm(VII)can be partially reduced to a black insoluble precipitate by aerobic cultures of Escherichia coli,and trapped intracellularly.However,188Re(VII)cannot be reduced and trapped,because of its lower oxidizing power of perrhenate as compared with pertechnetate or other reasons.
^99Tc^m is the most commonly used diagnostic radioisotope. And ^188Re is an excellent therapeutic radioisotope with a gamma photon for imaging. Both locate in the same group and have very similar properties. ^99Tc^m（Ⅶ） can be parfially reduced to a black insoluble precipitate by aerobic cultures of Escherichia coli, and trapped intracellularly. However, ^188Re（Ⅶ） cannot be reduced and trapped, because of its lower oxidizing power of perrhenate as compared with pertechnetate or other reasons.
基金
Supported by the Science&Technology Commission of Shanghai Municipality(No.06DZ19506)
the National Natural Science Foundation of China(No.20501022)
the Project of Knowledge Innovation of Chinese Academy of Sciences(No.KJCXI-SW-08)
关键词
放射性同位素
光子
治疗
大肠杆菌
埃希氏菌属
^99Tc^m,^188Re, Escherichia coli, Biological reduction, Intracellular trapping
