摘要
Objective: To investigate the clinical efficacy and immunological mechanism of herbal cake-partitioned moxibustion for aging process. Method: The herbal cake-partitioned moxibustion was adopted for 223 cases to observe the aging scores before and after the treatment. Apart from that, the T-lymphocyte subsets and changes of IL-2 and β-EP were also detected. Results: After treatment, the aging scores of 223 cases were all substantially reduced, along with an improvement of clinical symptoms, a strengthened cellular immune function, and an increase of total T-lymphocyte count. In addition, the CD4+/CD8+ ratio was restored normal, the synthesis or secretion of IL-2 was increased and the β-EP (as the neurotransmitter to modulate immune function) was substantially improved. Conclusion: The aging process is closely associated with the immune function. Moxibustion can modulate abnormal immune function and stabilize homeostasis and thus delay the aging process.
目的:探讨隔药饼灸抗衰老的临床疗效和免疫学机理。方法:采用隔药饼灸治疗223例老年人,观察隔药饼灸治疗前及治疗1疗程结束后衰老见症积分值,并检测血T淋巴细胞亚群、IL-2和β-内啡肽的变化。结果:223例老人经灸治后,衰老积分明显下降,在临床症状改善同时细胞免疫功能增强,T淋巴细胞总数增加,CD_4^+/CD_8^+比值恢复正常,IL-2合成分泌增加。β-EP作为免疫调节的神经介质,灸治后明显提高。结论:衰老过程与免疫功能密切相关。艾灸能纠正异常免疫状态、稳定机体内环境达到延缓衰老目的。