Clinical Observation on Treating Menopause Syndrome with Acupuncture Therapy

目的:研究针刺治疗更年期综合征的临床疗效及其内分泌机制。方法:47例更年期综合征患者分为针刺组32例(采用主穴肾俞、足三里、三阴交针刺治疗),对照组15例(采用口服谷维素治疗),观察两组治疗前后的Kupperman指数,进行疗效评价。并采用放射免疫分析法检测针刺组25例患者治疗前后血清E_2、T、FSH、LH含量变化。结果:针刺治疗能改善更年期综合征患者的临床症状,疗效优于对照组;针刺治疗后患者血清E_2含量明显升高,LH、T含量明显降低,FSH虽有下调趋势但无统计学意义。结论:针刺治疗更年期综合征疗效肯定。针刺治疗能够改善更年期综合征患者垂体-性腺轴的功能,该作用可能是其治疗更年期综合征的重要机制。

Objective： To study the clinical effect and the endocnne mechanism ot acupuncture therapy on menopause syndrome. Method： There were 47 cases with menopause syndrome, which were divided into two groups, 32 cases in the acupuncture group, treated by acupuncture with main acupoins of Shenshu （BL 23）, Zusanli （ST 36） and Sanyinjiao （SP 6）, and 15 cases in the control group, treated by orally taking the Oryzanol. The Kupperman index of the two groups was observed before and after treatment for evaluating the therapeutic effect. The changes of blood-serum E2, T, FSH, LH of the 25 cases in the acupuncture group were tested by radioimmunoassay before and after the treatment. Results： The acupuncture therapy can relieve the clinical symptoms of menopause syndrome, and its therapeutic effect was better than Oryzanol. After being treated by acupuncture therapy, the content of blood-serum E2 obviously increased, while the contents of LH and T declined, and the FSH also had a tendency to lower, but it was not statistically significant. Conclusion： The therapeutic effect of acupuncture therapy for menopause is confirmed. The acupuncture therapy can improve the function of hypophysial-gonadal axis of the patient with menopause syndrome, which may be the main mechanism of the acupuncture therapy for treating menopause syndrome.