子宫腺肌病与子宫肌瘤的临床特点及实验室检查比较分析

Comparative Analysis on Clinical Characteristics and Laboratory Detections between Adenomyosisand Hysteromyoma

目的:探讨子宫腺肌病与子宫肌瘤的临床特点及实验室检查,提高对子宫腺肌病术前确诊率。方法:选择52例子宫腺肌病患者和63例子宫肌瘤患者为研究对象,并对临床症状、妇科检查、B超结果及血清CA125水平进行比较。结果:两组患者发病年龄和临床症状相近,但子宫腺肌病的痛经症状明显(P<0.01);妇科检查子宫腺肌病的子宫常均匀性增大,且一般增大<12孕周,而宫体压痛明显高于子宫肌瘤(P<0.01);两组B超诊断符合率分别为59.6%和91.2%,有显著差异(P<0.05);子宫腺肌病组血清CA125阳性率79.8%,子宫肌瘤组血清CA125阳性率4.1%,有显著差异(P<0.01)结论:综合分析子宫腺肌病与子宫肌瘤的临床表现、妇科检查、B超所见和血清CA125水平有助于提高子宫腺肌病的术前诊断。

Objective： To investigate the clinical characteristics and laboratory detections between the adenomyosis and hysteromyoma. Methods： 52 cases of adenomyosis and 63 cases ofhysteromyoma were selected. A comparative study was conducted over their ages of the onset, clinical manifestations, results of ultrasound B and levels of serum CA125. Results： The two groups of patients were similar in age of onset and clinical manifestations. However, dysmenorrhea was more prominent in the group of adenomyosis than in hysteromyoma. There was significant difference （P〈0.01）. Physical examine of gynecology showed that uterine enlargement in adenomyosis group was homogeneous and less than enlargement of 12 weeks＇ pregnancy and that uterine body tender was more prominent than in hysteromyoma group （P〈0.01）. The accuracies of B-ultrasonic were 59.6 % and 91.2 % for adenomyosis and hysteromyoma, respectively. Such difference was statistically significant （P〈 0.05）. In adenomyosis group, the level of serum CA125 was increased evidently and the positive rate was 79.8 %, much higher than that in hysteromyoma group （4.1%, P〈0.01）. Conclusions： The diagnosis accuracies of the adenomyosis and hysteromyoma can be improved by analyzing synthetically the clinical characteristics and the laboratory detections.