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糖原合成酶激酶-3在胃肠道肿瘤的作用及其研究进展 被引量:1

Function and advance of GSK-3 in gastrointestinal tract tumor
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摘要 糖原合成酶激酶-3(GSK-3)是一种多功能的丝氨酸/苏氨酸蛋白激酶。实验证实,GSK-3通过多种途径在胃肠道肿瘤的生长、增殖及凋亡等方面起重要作用。现就近年来GSK-3在胃肠道肿瘤的研究进展作一综述。 Glycogen synthase kinase-3 (GSK-3)is a sort of multifunctional serine/threonine protein kinase. Some experiments have proved that GSK-3 plays an important role in promoting the cell growth,proliferation and apoptosis in gastrointestinal tract tumor. Now a review is made to summarize the function and advances of GSK 3 in gastrointestinal tract tumor in recent years.
作者 张靖 张庆瑜
出处 《国际消化病杂志》 CAS 2009年第1期17-19,28,共4页 International Journal of Digestive Diseases
基金 天津市自然科学基金资助项目(07JCZDJC07700)
关键词 糖原合成酶激酶-3 胃肠道肿瘤 治疗靶点 GSK-3 Gastrointestinal tract tumor Therapy target
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