半边莲中黄酮类化学成分研究

Studies on chemical constituents of flavones from Lobelia chinensis Lour

目的对半边莲中的黄酮类成分进行研究。方法使用稀醇进行提取,采用各种柱色谱法及重结晶法进行分离纯化,各种光谱、波谱技术进行结构鉴定。结果分离得到9个黄酮类化合物,经鉴定为:芹菜素(1)、木犀草素(2)、香叶木素(3)、白杨黄酮(4)、橙皮苷(5)、木犀草素-7-O-β-D-葡萄糖苷(6)、芹菜素-7-O-β-D-葡萄糖苷(7)、蒙花苷(8)、香叶木苷(9)。结论所分离得到的9个黄酮类化合物均为首次从半边莲中分离得到。

Objective To study the chemical constituents of flavones in Lobelia chinensis Lour. Method The chemical constituents of flavones in Lobelia ehinensis Lour were extracted with 70% ehtonal and isolated by various coloumn chromatography and recrystallization, and identified by various kinds of spectroscopic methods. Results 9 flavanoids were isolated and identified as apigenin （ 1 ）, loteolin （2）, Diosmetin （3）, chrysoeriol（4）,hesperidin（5）,loteolin-7-O-β-D-glucoside（6）,apigenin-7-O-β-D-glucoside（7）,linarin（8） and diosmin（9）. Conclusion All of these compouds were obtained from Lobelia chinensis Lour. for the first time.