TCR多样性及其在HIV-1感染控制中的作用研究进展
摘要
TCR识别特异性抗原多肽-MHC复合体，在共刺激分子协同作用下，启动细胞免疫应答，发挥抗病毒感染作用。HIV-1感染造成机体TCR分布异常，影响CTL的抗病毒效应。但针对某些特殊表位的TCR反应能够对HIV—1的感染起到一定的控制作用。高效抗逆转录病毒治疗（HAART）能够增加TCR多样性，使免疫系统功能得到部分恢复。
出处
《国际病毒学杂志》
2009年第1期16-19,共4页
International Journal of Virology
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