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乙型肝炎病毒基因型与耐拉米夫定变异的研究进展 被引量:1

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摘要 由于病毒自发变异的存在,人们将乙型肝炎病毒分成不同的基因型。各基因型HBV在区域分布、致病性和疗效反应等方面都具有一定的差异。拉米夫定是一种嘧啶类核苷类似物,它可以有效抑制乙型肝炎病毒的复制,但是长期使用容易产生耐药。关于乙型肝炎病毒基因型与耐拉米夫定变异之间的相关性,国I勺外的研究结果还尚不一致,本文将这方面的研究做一综述。
出处 《国际病毒学杂志》 2009年第1期30-32,F0003,共4页 International Journal of Virology
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