针药结合治疗肾虚痰瘀型多囊卵巢综合征疗效观察

Observation on therapeutic effect of acupuncture combined with Chinese herbs on polycystic ovary syndrome of kidney deficiency and phlegm stasis type

目的:观察针药结合治疗肾虚痰瘀型多囊卵巢综合征的临床疗效,并探讨其机制。方法:将63例符合肾虚痰瘀型多囊卵巢综合征患者随机分为针药结合组32例,采用针刺(穴取气海、关元等)和口服中药的方法治疗;单纯中药组31例,采用口服中药的方法治疗(用药同针药结合组)。比较两种治疗方法的临床疗效和相关性激素卵泡刺激素(follicle stimulating hormone,FSH)、黄体生成素(luteotropic hormone,LH)、睾酮(testosterone,T)及LH/FSH值的变化。结果:针药结合组总有效率93.8%,单纯中药组总有效率80.6%,针药结合组优于单纯中药组(P<0.05);在相关性激素指标上,针药结合组对T值的降低影响明显优于单纯中药组(P<0.01)。结论:针药结合治疗肾虚痰瘀型多囊卵巢综合征在临床疗效及降低性激素T值方面均优于单纯中药组,提示该法是治疗肾虚痰瘀型多囊卵巢综合征较好的一种方法。

Objective To observe the clinical therapeutic effect of acupuncture combined with Chinese herbs on polycystic ovary syndrome of kidney deficiency and phlegm stasis type and probe into the mechanism. Methods Sixty-three cases of polycystic ovary syndrome of kidney deficiency and phlegm stasis type were randomly divided in-to a combined acupuncture and Chinese herb group （n=32） treated with acupuncture at Qihai （CV6）, Guanyuan （CV4） , et al. and oral administration of Chinese herbs, and a simple Chinese herb group （n=31） treated with oral administration of the same Chinese herbs as in the combined acupuncture and Chinese herb group. The therapeutic effects and changes of follicle stimulating hormone （FSH）, luteotropic hormone （LH）, testosterone （T） and LH/ FSH were compared between the two groups. Results The total effective rate was 93.8 % in the combined acupuncture and Chinese herb group and 80.6% in the simple Chinese herb group, the former being significantly better than the latter （P〈0.05）. The decrease of T in the combined acupuncture and Chinese herb group was significantly superior to that in the simple Chinese herb group （P〈0.01）. Conclusion Acupuncture combined with Chinese herb therapy is superior to the simple Chinese herb in the clinical therapeutic effect on polycystic ovary syndrome of kidney deficiency and phlegm stasis type and decrease of T level, indicating this method is a better one for polycystie ovary syndrome of kidney deficiency and phlegm stasis type.