摘要
目的:优化板蓝根提取工艺条件。方法:以尿苷、鸟苷、腺苷的总含量为指标,采用正交试验对板蓝根水提工艺的加水量、回流次数、回流时间进行研究。结果:最佳提取条件为:用6倍量水回流提取3次,每次1h,上述3种核苷转移率为90.02%。结论:本工艺3种核苷总量的提取转移率较高,且工艺稳定性好,重现性好。
Objective : To optimize the extraction process for radix isatidis. Methods : The process was studied by orthogonal design with the total content of guanosine, uridine, and adenosine as the detective markers. Resuits:The optimized extraction condition was obtained. The crude material was extracted 3 times with 6 times volume of water for 1 h. The extraction rate of the three nucleosides was 90.02% in the process above. Conclusion: The high extraction rate of nucleosides was obtained with high stability and reproducibility.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2009年第4期353-355,375,共4页
Chinese Journal of New Drugs
关键词
板蓝根
核苷
提取工艺
正交试验
radix isatidis
nucleosides
extraction
orthogonal design