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靶向人端粒酶逆转录酶启动子在肿瘤基因治疗中的研究进展 被引量:3

Research Progress in Targeting Human Telomerase Reverse Transcriptase (hTERT) Promoter in Cancer Gene Therapy
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摘要 人端粒酶逆转录酶(hTERT)启动子具有在端粒酶阳性的肿瘤细胞中特异高表达的特点,使其成为肿瘤基因治疗较为理想的靶点。国内外学者利用hTERT启动子构建靶向肿瘤细胞的特异性表达载体也已经取得了较大进展。全文就hTERT启动子靶向治疗肿瘤的一些策略作一综述。
作者 刘燕 邓志华
出处 《肿瘤学杂志》 CAS 2009年第2期150-152,共3页 Journal of Chinese Oncology
基金 国家自然科学基金(30672405)
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