丝裂霉素联合顺铂治疗蒽环类及紫杉类耐药晚期乳腺癌23例

Mitomycin Combined with Cisplatin in the Treatment of 23 Cases with Anthracycline and Taxane-Resistant Advanced Breast Cancer

23例晚期乳腺癌以丝裂霉素联合顺铂进行化疗：丝裂霉素8mg／m^2静推，d1；顺铂25mg／m^2静滴，d1-3，每21d为1个疗程，化疗2个疗程后评价疗效．CR1例，PR3例，NC6例，PD13例，总有效率43．5％。主要毒副反应为骨髓抑制、消化道反应等。