320例甲状腺细针细胞学检查的临床分析

Analysis for 320 Fine Needle Aspiration Cytology of Hashimoto's Thyroiditis

总结该院门诊6年甲状腺细针细胞学穿刺的320例患者的临床表现.对实验室检查及穿刺结果进行分析,结果显示.抗甲状腺球蛋白抗体(TGAB)和抗甲状腺做粒体抗体(TMAB)滴定度的敏感性为84.8%.特异性为40%,精确度为83.4%.阳性预测值97.8%,阴性预测值7.8%:并根据慢性淋巴细胞性甲状腺炎(Hashimoto's thyroditis,HT)涂片腺上皮细胞的变性程度进行分型,通过与TMAB滴定度的随机抽样数据之间进行相关回归分析.得出相关系数r=0.4065.说明两者呈正相关。认为HT患者进行TGAB和TMAB以及甲状腺功能状态检查作筛选外,还需做细针抽吸细胞学并分型.有助于提高诊断的准确性。

The author summarized the clinic symptoms, laboratory examination and fine needle aspiration cytology (FNAC) of 320 outpatients during 6 years. The results showed that sensitivity, speciality, accuracy, PPV and NPV of both TGAB and TMAB were 84.4%,40% ,83.4% ,97.8%and 7.8% respectively in diagnosis of HT. The smears of HT were classified according to the degree of degeneration of adenoidal cells. The coefficient of correlation r=0.4065 was obatined by means of regressive correlation analysis between the classified types of smears of HT and the random data of TMAB. The result demonstrated positive correlation between the types of smears and the titer of TMAB. The higher the titer of antibody, the more typical the smear. The author considered that FNAC was beneficial in raising the accuracy of HT besides TGAB, TMAB and FT3,FT4, sTSH.