宫内节育器首置失败者再置GyneFix宫内节育器的效果观察

Investigating the effect of second replacing GyneFix introuterine device in reproductive age women after first failure at placing introuterine device

目的:探讨首次放置宫内节育器失败的育龄妇女再次放置GyneFix宫内节育器的效果。方法:将109例有放置宫内节育器失败史的育龄女性随机分为GyneFix组(n=56)和VCu200组(n=53)。前者放置GyneFix、后者放置VCu200宫内节育器,于置器后6、12个月随访,对放置效果进行评价。结果:置器后6个月,GyneFix组的IUD的终止率明显低于VCu200组(P=0.038),而续用率则GyneFix组明显高于VCu200组(P=0.038)。放置后12个月,GyneFix组脱落率明显低于VCu200组(P=0.038);同样,GyneFix组总的终止率明显低于VCu200组(P=0.021),但是前者续用率明显高于后者(P=0.021)。而带环妊娠则6个月和12个月时均无显著性差异。结论:GyneFix宫内节育器避孕效果可靠、可接受性好,对首次置器失败者推荐使用GyneFix宫内节育器。

Objective： To investigate the effect of GyneFix introuterine device in reproductive age women after first failure at placing introuterine device（IUD）. Methods： 109 reproductive age women who had failure to receive IUD for the first time were randomly divided into GyneFix group （n=56） and VCu200 group （n=53）.The women in GyneFix group were received GyneFix IUD,while in VCu200 group were received VCu200 IUD.The effect of placed IUD were analyzed after 6 months or 12 months. Results： After 6 months of placement,the terminative percentage of GyneFix IUD was significantly lower than VCu200 IUD （P=0.038）,but the continuously using percentage of GyneFix IUD was remarkably higher than VCu200 IUD （P=-0.038）.After 12 months,the status was found similar to that of after 6 months except the percentage of IUD defluxion in GyneFix group was significantly lower than that of in VCu200 IUD （3.6% vs 15.1%, P=0.038 ）. Conclusion： GyneFix I-UD is efficient and feasible in reproductive age women who had failure to receive IUD for the first time.