胆酸甲酯甲基丙烯酸酯类衍生物的合成与聚合特性

Preparation and Polymeric Properties of Methacryloyl Derivatives of Cholic Acid Methyl Ester

以甲基丙烯酰氯为酰化试剂,三乙胺为缚酸剂对胆酸甲酯进行修饰,合成了分子中含有1～3个甲基丙烯酰基的胆酸衍生物;应用溶液聚合方法研究了产物的聚合特性.结果显示:在实验条件下,胆酸甲酯甲基丙烯酰基衍生物在溶液中只有C3位的C C发生聚合反应,C7和C12位的C C不发生聚合反应.

Methacryloyl derivatives ofcholic acid methyl ester with 1-3 carbon-carbon double bonds have been synthesized by the use of methacryloyl chloride as acylating reagents,triethylamine as acid-binding reagent. The polymeric properties of those monomers were studied by solution polymerization. On the experiment conditions,the polymeric reaction only happened on C3 position carbon-carbon double bond of the products,not on C7 and C12 positions carbon-carbon double bonds of them.