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肾功能与剂量调整 被引量:5

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摘要 肾在药物代谢中起重要作用。在肾功能不全时,由于水溶性药物和药物的代谢产物清除率降低,如按常规用药会导致血药浓度过高,必须根据药物清除率下降的程度进行剂量个体化处理,尤其对于治疗窗较窄的药物更为重要。
出处 《今日药学》 CAS 2009年第2期14-16,共3页 Pharmacy Today
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